So first of all, before beginning the Śrīmad-Bhāgavatam, the author is offering respectful obeisances to the Supreme Personality of Godhead. The Supreme Personality of Godhead is explained in the following four lines. The first line is janmādy asya yataḥ, means Supreme Personality of Godhead is the origin of all emanation. The human mind is inquisitive. A human being, even a child, he enquires from his father. We have got experience personally. Any intelligent boy, he enquires from the father. He is inquisitive. That is human life. He enquires, "What is this, father? What is this father?" And the father replies. So unless this enquiry is there, he is not human being. A cat and dog cannot enquire about the origin of a thing. But a human mind is developed in such a way that he enquires, he makes research to find out the original cause. Just like nowadays the scientists are enquiring about the origin of life. But unfortunately, they are finding out the original cause which is not. Just like they are trying to research out what is the origin of life. And there are many, many learned scientists. They think that the origin of life is chemical combination. So that is not the fact.
Therefore, without being guided by authority, nobody can find out the perfect answer of an enquiry. Even in the university level, those who are research scholar, they are guided by three experienced professors. And when the student's research work is admitted by the three professors, then he is awarded the doctorate designation. So the, as I have already said, the child enquires, "What is this, father?" Similarly, we should also enquire, "What is the origin of this universe?" Not only universe, but any item within our experience, naturally we are inclined... Just like here is a microphone. So an intelligent person is inquisitive to enquire, "Who is the manufacturer of this microphone?" Just like we enquire about a child, "Whose son he is? Who is his father?" similarly, this is human mind, to enquire about the origin. That is the only business of human being. In the Śrīmad-Bhāgavatam it is said, jīvasya tattva-jijñāsā, means the jīva, means human being especially... Jīva means all living being, but above all living beings, the human being is the most awakened consciousness. Therefore his business is to enquire about the Absolute Truth. It is said, jīvasya tattva-jijñāsā.
Prabhupada's lecture - Śrīmad-Bhāgavatam 1.1.1 - Caracas, February 20, 1975